torque teno midi virus/small anellovirus in sera of healthy, hiv/hcv and hiv infected individuals in lorestan province, iran

نویسندگان

maryam fatholahi department of biology, faculty of sciences, university of isfahan, isfahan, ir iran

majid bouzari department of biology, faculty of sciences, university of isfahan, isfahan, ir iran; department of biology, faculty of sciences, university of isfahan, p. o. box: 8174673441, isfahan, ir iran. tel: +98-3117932459, fax: +98-3117932456

چکیده

conclusions although significant differences (p < 0.01) were observed in the frequency of ttmdv/sav between healthy controls and each of the hiv positive and hiv/hcv co-infected individuals, no significant difference was observed between hiv positive and hiv/hcv co-infected cases, which may be due to hiv associated immunodeficiency. this is the first time that ttmdv/sav is reported in hiv infected individuals worldwide. interpretation of the high frequency of the virus (82.7%) in hiv cases needs more detailed studies. results in the hiv/hcv, hiv/hcv/hbv, hiv, and control cases, 29 (80.5%), 3 (75%), 43 (82.7%), and 16 (14.5%) were positive for dna of ttmdv/sav, respectively. in the hiv/hcv infected cases and hiv positive cases the level of alanine aminotransferase (alt) and aspartate aminotransferase (ast) were not significantly different in ttmdv/sav infected and non-infected individuals (p > 0.05). materials and methods fifty two, 36, 4, and 110 serum samples from hiv positive, patients with hiv/hcv and hiv/hcv/hbv co-infections, and healthy individuals were collected in khorramabad city, respectively. nested-polymerase chain reaction was performed using smas/smar primers to detect ttmdv/sav dna. serum aminotransferases were measured. background torque teno midi virus/small anellovirus (ttmdv/sav) is a member of the gammatorquevirus genus within the family anelloviridae. it is detected in healthy, hepatitis b virus, hepatitis c virus and hiv infected individuals and also patients with acute respiratory disease in different countries, but its role in clinical diseases and its full geographical distribution is still unclear. objectives the current study aimed to detect the frequency of infection with ttmdv/sav in the sera of healthy blood donors, hepatitis c infected and hiv positive individuals in lorestan province, iran; and also investigate the possible role of ttmdv/sav virus in liver diseases.

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Torque Teno Midi Virus/Small Anellovirus in Sera of Healthy, HIV/HCV and HIV Infected Individuals in Lorestan Province, Iran

BACKGROUND Torque Teno Midi Virus/Small Anellovirus (TTMDV/SAV) is a member of the Gammatorquevirus genus within the family Anelloviridae. It is detected in healthy, Hepatitis B Virus, Hepatitis C Virus and HIV infected individuals and also patients with acute respiratory disease in different countries, but its role in clinical diseases and its full geographical distribution is still unclear. ...

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Detection of Torque teno midi virus/Small anellovirus (TTMDV/SAV) in the sera of domestic village chickens and its vertical transmission from hen to eggs.

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detection of torque teno midi virus/small anellovirus (ttmdv/sav) in the sera of domestic village chickens and its vertical transmission from hen to eggs

although the infection of different animals and non-human primates with other members of anelloviridae have already been reported there is no report about infection of animals with torque teno midi virus/small anellovirs (ttmdv/sav). the aim of this study was to detect the virus in domestic village chickens. blood samples were collected from 79 domestic village chickens in isfahan. blood sample...

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عنوان ژورنال:
jundishapur journal of microbiology

جلد ۸، شماره ۱۱، صفحات ۰-۰

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